A region within synthetic peptide: GGYGDNLGGG QMYSPREMRA NGSWQEAVTP SSVTSPTEGP GSVHSDTSN, corresponding to C terminal amino acids 382-430 of Human PBX2
Conjugate
Unconjugated
Applications
Application Notes
WB: 1.25 μg/ml.
Target
Alternative Names
PBX2; pre-B-cell leukemia homeobox 2; pre B cell leukemia transcription factor 2; pre-B-cell leukemia transcription factor 2; G17; HOX12; PBX2MHC; homeobox 12; homeobox protein PBX2;
PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family and was identified by its similarity to a homeobox gene involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter, binding to the sequence 5-ATCAATCAA-3. It forms heterodimers with MEIS1, involved in activation of PF4 transcription, and heterotrimers with MEIS1 and HOXA9. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
Citations
Publication ()
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