Specificity: PAX8 Antibody detects endogenous levels of total PAX8.
Host: Rabbit
Application: WB, IHC
Species Reactivity: Human, Mouse, Rat; Predicted: Dog
Summary
Specifications
Antibody Isotype
IgG
Species Reactivity
Human; Mouse; Rat
Immunogen
A synthesized peptide derived from human PAX8, corresponding to a region within N-terminal amino acids.
Conjugate
Unconjugated
Applications
Application Notes
WB 1:500-1:2000 IHC 1:50-1:200
General Notes
This product (Catalog No. DPABH-02271) is a rabbit-derived polyclonal antibody raised against human PAX8. This antibody exhibits cross-reactivity with PAX8 from mouse and rat. It has been affinity purified by Protein A. This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. DPABH-02271 is suitable for use in WB 1 (500-1:2000), IHC 1 (50-1:200) applications. DPABH-02271 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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