Anti-PANK4 (aa 50-100) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide, corresponding to a region within amino acids 50-100 of Human PANK4 (NP_060686.1).

Conjugate

Application Notes

WB: 1/2000 - 1/10000; IP: 2-10 μg/mg lysate.

Alternative Names

PANK4; pantothenate kinase 4; FLJ10782; hPanK4; pantothenic acid kinase 4; DKFZp547M242;

Entrez Gene ID

Antigen Description

PANK4 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the physiological regulation of the intracellular coenzyme A (CoA) concentration. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.

Pathway

Coenzyme A biosynthesis; Coenzyme A biosynthesis, pantothenate =>CoA; Metabolic pathways; Metabolism;