Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human PAIP2.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
PAIP2; poly(A) binding protein interacting protein 2; polyadenylate-binding protein-interacting protein 2; PAIP2A; PAIP-2; PABP-interacting protein 2; PABC1-interacting protein 2; polyA-binding protein-interacting protein 2; poly(A)-binding protein-intera
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Citations
Publication ()
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COA
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