Anti-PADI3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PADI3 is used for rabbit immunization.

Conjugate

Alternative Names

PADI3; peptidyl arginine deiminase, type III; protein-arginine deiminase type-3; PDI3; peptidylarginine deiminase III; protein-arginine deiminase type III; PAD3; MGC126307; MGC126308;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.

Pathway

protein citrullination, organism-specific biosystem; protein citrullination, conserved biosystem;