General Notes
This product (Catalog No. DPABH-13304) is a rabbit-derived polyclonal antibody raised against human OR4A16. It has been affinity purified by Protein A. OR4A16 is a protein-coding gene in humans that encodes the olfactory receptor protein OR4A16, a seven-transmembrane G protein-coupled receptor (GPCR) responsible for detecting odorant molecules in the nasal cavity to initiate neuronal signaling for smell perception. Located on the forward strand of chromosome 11 at position 11q11 (GRCh38.p14 assembly: NC_000011.10 (55,343,201-55,344,187)), the gene spans approximately 987 base pairs and consists of a single exon, reflecting the typical structure of olfactory receptor genes. Olfactory receptors, including OR4A16, form the largest multigene family in the human genome, comprising over 400 functional genes that share structural similarities with receptors for neurotransmitters and hormones. Upon binding odorants, OR4A16 activates G proteins to transduce signals via the olfactory signaling pathway, ultimately leading to the activation of olfactory sensory neurons and the brain's interpretation of scents. The protein's existence is inferred from homology to other olfactory receptors, with an annotation score of 3 out of 5, and it is primarily expressed in the olfactory epithelium of the nose.
DPABH-13304 is suitable for use in WB 1 (500-1:1000), IF/ICC 1 (100-1:500) applications.
DPABH-13304 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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