General Notes
This product (Catalog No. DPABH-14088) is a rabbit-derived polyclonal antibody raised against human OR10S1. It has been affinity purified by Protein A. OR10S1 is a protein-coding gene in Homo sapiens that encodes the olfactory receptor 10S1, a member of the large family of G-protein-coupled receptors (GPCRs) responsible for odor detection in the nose. This receptor interacts with odorant molecules to initiate a neuronal response, triggering the perception of smell through G protein-mediated signal transduction. The gene consists of a single coding exon and produces a protein with a characteristic seven-transmembrane domain structure shared by many neurotransmitter and hormone receptors. Located on the long arm of chromosome 11 at cytogenetic band 11q24.1, specifically from base pair 123,976,661 to 123,977,781 (GRCh38.p14 assembly, reverse strand), OR10S1 is part of the expansive olfactory receptor gene family, the largest in the human genome. Also known by the alias OR11-279, it has been validated through RefSeq and is conserved across several mammalian species. Like other olfactory receptors, OR10S1 is predicted to play a role in chemosensory processes, though expression data are limited. Some studies suggest ectopic expression in non-olfactory tissues such as the colon. A known ligand is lilial.
DPABH-14088 is suitable for use in WB 1 (500-1:1000), IF/ICC 1 (100-1:500) applications.
DPABH-14088 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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