Anti-OPN1MW monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human OPN1MW is used for rabbit immunization.

Conjugate

Alternative Names

OPN1MW; opsin 1 (cone pigments), medium-wave-sensitive; CBBM, CBD, color blindness, deutan , GCP, green cone photoreceptor pigment; medium-wave-sensitive opsin 1; COD5; cone dystrophy 5 (X linked); OPN1MW1; green cone pigment; green-sensitive opsin; photo

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.

Pathway

Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Opsins, organism-specific biosystem; Signal Transduction, organism-specific biosystem.