Anti-NXPE4 polyclonal antibody (DPABH-22306)

Rabbit anti-Human NXPE4 (aa 407-456) polyclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to a region within C terminal amino acids 407-456 (TYSVKEMEYL TRAIDRTGGE KNTVIVISLG QHFRPFPIDV FIRRALNVHK) of Human FAM55D (NP_001071107).
Conjugate
Unconjugated

Applications


Application Notes
WB: 5 μg/ml; IHC-P: 4 - 8 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
NXPE4; neurexophilin and PC-esterase domain family, member 4; FAM55D; C11orf33; NXPE family member 4; protein FAM55D
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3 ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. The function about NXPE4 antigen include molecular_function.

Citations


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