Full length protein, corresponding to amino acids 1-405 of Human FAM55A Isoform 2 (NP_689528.1).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
NXPE1; neurexophilin and PC-esterase domain family, member 1; FAM55A; NXPE family member 1; protein FAM55A; family with sequence similarity 55, member A;
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]
Citations
Publication ()
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