Specifications
Immunogen
A synthetic peptide corresponding to human NUP62. The sequence is C-RKEQERSFRITFD
Applications
Application Notes
ELISA: 1:8000. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
NUP62; nucleoporin 62kDa; p62; IBSN; SNDI; nuclear pore glycoprotein p62; nucleoporin 62kD; nucleoporin Nup62; 62 kDa nucleoporin;
Product Background
Antigen Description
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.
Pathway
Antiviral mechanism by IFN-stimulated genes; Cell Cycle, Mitotic; Disease; Gene Expression
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Pendergrass, KD; Gwathmey, TM; et al. The angiotensin II-AT1 receptor stimulates reactive oxygen species within the cell nucleus. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 384:149-154(2009).
Munier, S; Rolland, T; et al. Exploration of Binary Virus-Host Interactions Using an Infectious Protein Complementation Assay. MOLECULAR & CELLULAR PROTEOMICS 12:2845-2855(2013).
COA
Certificate of Analysis
