This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Pathway
Antiviral mechanism by IFN-stimulated genes; Cell Cycle; Cytokine Signaling in Immune system; Disease; Export of Viral Ribonucleoproteins from Nucleus; Gastric cancer network 1; Gene Expression; Glucose transport
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