Anti-NTF4 (aa 111-209) polyclonal antibody

Species Reactivity

Human

Immunogen

NTF5 (NP_006170, 111 a.a. ~ 209 a.a) partial recombinant protein with GST tag. The sequence is VDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSEC KAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR

Conjugate

Alternative Names

NTF4; neurotrophin 4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5; neurotrophin-4; neurotrophin-5; neutrophic factor 4; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5 (neurotrophin 4/5);

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.

Pathway

MAPK signaling pathway; Neurotrophic factor-mediated Trk receptor signaling; Neurotrophin signaling pathway;