Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human NR1D1 aa 550 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: P20393
Applications
Application Notes
ICC/IF: 1/100 - 1/250; IHC-P: 1/50 - 1/100; WB: 1/1000 - 1/5000.
Target
Alternative Names
NR1D1; nuclear receptor subfamily 1, group D, member 1; THRAL; nuclear receptor subfamily 1 group D member 1; ear 1; hRev; Rev ErbAalpha; THRA1; Rev-ErbAalpha; rev-erbA-alpha; V-erbA-related protein 1; nuclear receptor Rev-ErbA-alpha; EAR1; ear-1;
Product Background
Antigen Description
Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.
Pathway
BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; Circadian rhythm pathway, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem;
Citations
Publication ()
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