Anti-NPHP4 (internal region) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide derived from internal sequence of Human Nephrocystin 4.

Conjugate

Application Notes

IHC-P: 5 μg/ml;

Alternative Names

NPHP4; nephronophthisis 4; POC10; SLSN4; nephrocystin-4; nephroretinin; POC10 centriolar protein homolog;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

Pathway

Signal Transduction;