Anti-NMT1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human NMT1 is used for rabbit immunization.

Conjugate

Alternative Names

NMT1; N-myristoyltransferase 1; glycylpeptide N-tetradecanoyltransferase 1; alternative; short form NMT S; long form; NMT L; myristoyl CoA:protein N myristoyltransferase; NMT; NMT 1; long form, NMT-L; alternative, short form NMT-S; type I N-myristoyltrans

Entrez Gene ID

UniProt ID

Antigen Description

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).

Pathway

Activation, myristolyation of BID and translocation to mitochondria, organism-specific biosystem; Apoptosis, organism-specific biosystem; Assembly of HIV virion, organism-specific biosystem; Disease, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem; Intrinsic Pathway for Apoptosis, organism-specific biosystem.