Anti-NMNAT2 (aa 100-200) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Rat

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Rat NMNAT2.

Conjugate

Application Notes

WB: 1 μg/ml; ICC/IF: 5 μg/ml.

Alternative Names

NMNAT2; nicotinamide nucleotide adenylyltransferase 2; nicotinamide mononucleotide adenylyltransferase 2; NMN adenylyltransferase 2; naMN adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 1;

Entrez Gene ID

UniProt ID

Antigen Description

Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannnot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).

Pathway

Metabolic pathways; Metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; Nicotinate and nicotinamide metabolism; Nicotinate metabolism;