Anti-NME1 (aa 1-152) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human

Immunogen

Recombinant fragment, corresponding to a region within amino acids 1-152 of Human NM23A (Uniprot ID: P15531).

Conjugate

Application Notes

WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/1000;

Alternative Names

NME1; NME/NM23 nucleoside diphosphate kinase 1; NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; nucleoside diphosphate kinase A; NDP kinase A; granzyme A-activated DNase; metastasis inhibition factor nm23; tumor metastatic process-associated prote

Entrez Gene ID

UniProt ID

Antigen Description

Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.

Pathway

Adenine ribonucleotide biosynthesis, IMP => ADP,ATP; Arf6 downstream pathway; CMP phosphorylation; Guanine ribonucleotide biosynthesis IMP => GDP,GTP