Anti-NLRP12 (N-terminal) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

NALP12 antibody was raised against an 18 amino acid peptide near the amino terminus of human NALP12.

Conjugate

Alternative Names

NLRP12; NLR family, pyrin domain containing 12; RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3; NACHT, LRR and PYD domains-containing protein 12; monarch 1; regulated by nitric oxide; PYRIN-containing APAF1-like protein 7; nucleotide-binding oligomerizat

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Pathway

NOD pathway