Recombinant protein fragment corresponding to human NKX2-2.
Conjugate
Unconjugated
Applications
Application Notes
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
NKX2-2; NK2 homeobox 2; NK 2 (Drosophila) homolog B , NK2 transcription factor related, locus 2 (Drosophila) , NKX2B; homeobox protein Nkx-2.2; NKX2.2; NK-2 homolog B; homeobox protein NK-2 homolog B; NK2 transcription factor-like protein B; NK2 transcrip
The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Pathway
Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in beta cells, organism-specific biosystem; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-12575 in a publication? Let us know and earn a reward for your research.
Mastick, GS; Andrews, GL; et al. Pax6 regulates the identity of embryonic diencephalic neurons. MOLECULAR AND CELLULAR NEUROSCIENCE 17:190-207(2001).
Li, Q; Brus-Ramer, M; et al. Electrical stimulation of the medullary pyramid promotes proliferation and differentiation of oligodendrocyte progenitor cells in the corticospinal tract of the adult rat. NEUROSCIENCE LETTERS 479:128-133(2010).
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COA
Certificate of Analysis
