General Notes
This product (Catalog No. DPABH-00604) is a rabbit-derived polyclonal antibody raised against human NFE2L1, targeting the amino acid region 393–742 of the protein. This antibody exhibits cross-reactivity with Human NFE2L1 from mouse. It has been affinity purified by Protein A. NFE2L1, also named as HBZ17, NRF1, TCF11 and LCR-F1, belongs to the bZIP family and CNC subfamily. It activates erythroid-specific, globin gene expression. NFE2L1 is involved in mediating ascorbic acid-induced osterix expression and osteoblast differentiation via binding to the antioxidant response element of the osterix promoter. NFE2L1, produced by osteoblasts, is involved in regulating osterix expression, osteoblast differentiation, and bone formation. (PMID:19887580).
DPABH-00604 is suitable for use in Western blot (WB) (1:500–1:1,000), IF/ICC (1:200–1:800) applications.
DPABH-00604 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.