Anti-NDUFS6 (internal region) polyclonal antibody

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to amino acids at internal region of human NDUFS6. The sequence is C-RIRFVGRQKEVNEN

Conjugate

Application Notes

ELISA: 1:16000; WB: 0.01-0.03 μg/mL. & The optimal working dilution should be determined by the end user.

Alternative Names

NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); CI-13kA; CI13KDA; CI-13kD-A; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; complex I 13kDa subunit A; NADH:ubiquinone oxidoreductase NDUFS6

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]

Pathway

Alzheimers disease; Electron Transport Chain; Huntingtons disease; NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria