Specifications
Species Reactivity
Mouse; Rat; Cow; Human; C. elegans; Fruit fly; Zebrafish
Immunogen
Purified cow mitochondrial complex I.
Applications
Application Notes
WB: 0.5 - 1 μg/ml; Flow Cyt: 1μg/106 cells;
Target
Alternative Names
NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; CI-30kD; complex I-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit;
Product Background
Antigen Description
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Pathway
Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem; NAD/NADH phosphorylation and dephosphorylation mammals, organism-specific biosystem;
Citations
Publication ()
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COA
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