The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Pathway
Alzheimers disease; Electron Transport Chain; Huntingtons disease; Metabolism; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex; Non-alcoholic fatty liver disease (NAFLD); Oxidative phosphorylation; Parkinsons disease; Respiratory electron transport; Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. The citric acid (TCA) cycle and respiratory electron transport.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Li, YJ; Ao, H; et al. Stage-specific developmental gene expression of goat preimplantation embryos produced in vitro. TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES 35:15-19(2011).
Mishmar, D; Ruiz-Pesini, E; et al. Adaptive selection of mitochondrial complex I subunits during primate radiation. GENE 378:11-18(2006).
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