NCOA6 (NP_054790, 1954 a.a. ~ 2063 a.a) partial recombinant protein with GST tag. The sequence is VGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIP GRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK
Conjugate
Unconjugated
Target
Alternative Names
NCOA6; nuclear receptor coactivator 6; NRC; AIB3; ASC2; PRIP; TRBP; RAP250; NRC RAP250; PPAR-interacting protein; activating signal cointegrator 2; activating signal cointegrator-2; nuclear receptor coactivator RAP250; amplified in breast cancer protein 3
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Pathway
Activation of gene expression by SREBF (SREBP); Circadian Clock; Developmental Biology; Gene Expression.
Citations
Publication ()
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COA
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