Synthetic peptide corresponding to a region within internal sequence amino acids 266-315 (CTVNIMFGTP QEHRNMPQAD AMVLVARNYE RYKNECREKE REEIARQAAK) of Human NCOA5 (NP_066018).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
NCOA5; nuclear receptor coactivator 5; bA465L10.6; CIA; coactivator independent of AF 2; NCoA-5; coactivator independent of AF-2;
NCOA5 is a nuclear receptor coregulator that can have both coactivator and corepressor functions. It interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. It Is also involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c myc in response to 17 beta estradiol (E2).
Citations
Publication ()
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COA
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