Anti-MYL9 monoclonal antibody (DCABH-311)

Mouse anti-Chicken MYL9 monoclonal antibody for ICC/IF, Dot, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Clone
NZ-32
Species Reactivity
Chicken
Immunogen
Chicken lens membranes.
Conjugate
Unconjugated

Target


Alternative Names
MYL9; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin regulatory light polypeptide 9; LC20; MLC2
Entrez Gene ID
UniProt ID

Product Background


Gene summary
MYL9 (Myosin Light Chain 9) is a Protein Coding gene. Diseases associated with MYL9 include primary cutaneous amyloidosis. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. GO annotations related to this gene include calcium ion binding and structural constituent of muscle. An important paralog of this gene is MYLPF. Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.
Antigen Description
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin regulatory light polypeptide 9 is a protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. The function about MYL9 antigen include calcium ion binding; structural constituent of muscle.
Pathway
Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Muscle contraction, organism-specific biosystem.

Citations


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References


Chen, XY; Li, R; et al. Identification of differentially expressed genes in hypothalamus of chicken during cold stress. MOLECULAR BIOLOGY REPORTS 41:2243-2248(2014).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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