a synthetic peptide [(C)RHHRHRDRDKTSASTPA] corresponding to amino acids 851-867 of the α1B-subunit of rat brain voltage-gated calcium channels, conjugated to KLH
The N-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit forms the pore through which calcium enters the cell and determines most of the channel"s properties. The α1 subunit is also known as the calcium channel, voltage-dependent, N type, alpha 1B subunit (CACNA1B) or Cav2.2 which in humans is encoded by the CACNA1B gene.
Pathway
Calcium Regulation in the Cardiac Cell; Calcium signaling pathway; Cholinergic synapse; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels; Dopaminergic synapse; GABAergic synapse; MAPK signaling pathway; Neuronal System; Serotonergic synapse; Synaptic vesicle cycle; Taste transduction; Transmission across Chemical Synapses; Type II diabetes mellitus.
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