General Notes
This product (Catalog No. DPABH-13099) is a rabbit-derived polyclonal antibody raised against human MYC, targeting the amino acid region 351–437 of the protein. This antibody exhibits cross-reactivity with Human MYC from mouse and rat. It has been affinity purified by Protein A. MYC is a proto-oncogene that encodes a nuclear phosphoprotein functioning as a basic helix-loop-helix leucine zipper (bHLH-LZ) transcription factor, which heterodimerizes with MAX to bind E-box DNA sequences and regulate gene expression critical for cell cycle progression, metabolism, apoptosis, and cellular transformation. Located on chromosome 8q24.21 in humans, MYC is ubiquitously expressed across tissues, with particularly high levels in the gallbladder and esophagus, and belongs to a superfamily including MYCL and MYCN that collectively act as master regulators of cellular growth and differentiation.
DPABH-13099 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-13099 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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