Anti-MTF1 (aa 41-140) polyclonal antibody

Species Reactivity

Human

Immunogen

MTF1 (NP_005946, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. The sequence is GTVYDRTTVLIEQDPGTLEDEDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISP DQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRY

Conjugate

Alternative Names

MTF1; metal-regulatory transcription factor 1; ZRF; MTF-1; metal regulatory transcription factor 1; zinc regulatory factor; transcription factor MTF-1; MRE-binding transcription factor; MRE-binding transcription factor-1; metal-responsive transcription fa

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE).