Anti-MRPS16 (internal region) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide derived from internal sequence of Human MRPS16 (UniProt Q9Y3D3).

Conjugate

Application Notes

WB: 1/500 - 1/1000; IHC-P: 1/50 - 1/100.

Alternative Names

MRPS16; mitochondrial ribosomal protein S16; COXPD2; RPMS16; CGI-132; MRP-S16; 28S ribosomal protein S16, mitochondrial; S16mt;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.

Pathway

Ribosome;