Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-20244 in a publication? Let us know and earn a reward for your research.
Yoo, YA; Kim, MJ; et al. Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27(Kip1). MOLECULAR AND CELLULAR BIOLOGY 25:6603-6616(2005).
Preiherr, J; Hildebrandt, T; et al. Transcriptional profiling of human mammary carcinoma cell lines reveals PKW, a new tumor-specific gene. ANTICANCER RESEARCH 20:2255-2264(2000).
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