Rabbit Anti-Human MRPL23 Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

A synthesized peptide derived from human MRPL23

Conjugate

Application Notes

WB: 1:1000-3000

General Notes

This product (Catalog No. DPABH-14720) is a rabbit-derived polyclonal antibody raised against human MRPL23. This antibody exhibits cross-reactivity with MRPL23 from mouse and rat. It has been affinity purified by Protein A. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.
DPABH-14720 is suitable for use in Western blot (WB) (1:1,000–1:3,000) application.
DPABH-14720 is supplied as a liquid formulation in PBS containing 50% glycerol, and 0.02% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

MRPL23, L23MRP, L23mt, MRP-L23, Ribosomal protein L23-like, RPL23L

Entrez Gene ID

UniProt ID