Rabbit Anti-Human MRPL17 (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

A synthesized peptide derived from human MRPL17, corresponding to a region within the internal amino acids.

Conjugate

Application Notes

WB 1:1000-3000
IF/ICC 1:100-1:500

General Notes

This product (Catalog No. DPABH-03058) is a rabbit-derived polyclonal antibody raised against human MRPL17. This antibody exhibits cross-reactivity with MRPL17 from mouse. It has been affinity purified by Protein A. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
DPABH-03058 is suitable for use in WB 1 (1000-3000), IF/ICC 1 (100-1:500) applications.
DPABH-03058 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID