Recombinant human ABCC1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 918-1025 aa of NM_004996
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:1000 IHC: 1:50-1:500
General Notes
This product (Catalog No. DPABH-00428) is a rabbit-derived polyclonal antibody raised against human MRP1, targeting the amino acid region 918–1025 of the protein. It has been affinity purified by Protein A. Multidrug resistant-associated protein 1 (MRP1, also known as ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier. DPABH-00428 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications. DPABH-00428 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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