Anti-MPP5 (aa 79-177) polyclonal antibody

Species Reactivity

Human

Immunogen

MPP5 (NP_071919, 79 a.a. ~ 177 a.a) partial recombinant protein with GST tag. The sequence is LDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTL VDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKAS

Conjugate

Alternative Names

MPP5; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); PALS1; MAGUK p55 subfamily member 5; stardust; protein associated with lin seven 1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Cell junction organization; Cell-cell junction organization; Tight junction;