General Notes
This product (Catalog No. DPABH-22908) is a rabbit-derived polyclonal antibody raised against human MOCS1, targeting the amino acid region 90–290 of the protein. This antibody exhibits cross-reactivity with Human MOCS1 from mouse and rat. It has been affinity purified by Protein A. MOCS1 (Molybdenum cofactor synthesis 1), also known as MOCS1A, MOCS1B, MOCOD, plays a crucial role in the biosynthesis of molybdenum cofactor and molybdopterin, which are essential for the activity of several key enzymes involved in carbon, nitrogen, and sulfur metabolism. MOCS1 produces two functional proteins, MOCS1A and MOCS1B, which follow different translocation routes before mitochondrial matrix import for cPMP biosynthesis involving both proteins (PMID: 31996372). MOCS1 was tumor suppressor gene affecting survival positively, while the other genes were oncogenes whose high expression was associated with poor survival (PMID: 37120564). The MOCS1 protein exists multiple isoforms.
DPABH-22908 is suitable for use in Western blot (WB) (1:1,000–1:6,000), IF/ICC (1:50–1:500) applications.
DPABH-22908 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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