A synthetic peptide of human MGC29506 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
MZB1; marginal zone B and B1 cell-specific protein; PACAP; pERp1; MEDA-7; marginal zone B- and B1-cell-specific protein; HSPC190; caspase-2 binding protein; plasma cell-induced ER protein 1; proapoptotic caspase adapter protein; proapoptotic caspase adapt
MZB1 (marginal zone B and B1 cell-specific protein) is a protein-coding gene. Diseases associated with MZB1 include pheochromocytoma, and gastric cancer. GO annotations related to this gene include protein binding. Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
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