General Notes
This product (Catalog No. DPABH-15038) is a rabbit-derived polyclonal antibody raised against human METTL13, targeting the amino acid region 541–642 of the protein. It has been affinity purified by Protein A. Protein methyltransferase like 13 (METTL13), also called FEAT, is coded by gene METTL13, which is located at chromosome 1q24.3. Purified from rat livers in 2011 by a Japanese researcher, METTL13 was found to be abnormally overexpressed in several human cancers including lung cancer and to drive tumorigenesis in transgenic mice. A study indicated that METTL13 inhibits apoptosis of lung, breast and liver cancer cells and miR-16 can repress the expression of METTL13 by binding to its 3′-untranslated region. (PMID: 33985542).
DPABH-15038 is suitable for use in Western blot (WB) (1:500–1:1,000), IF/ICC (1:200–1:800) applications.
DPABH-15038 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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