Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
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Q: Could you give me more information about the buffer formulation used in Anti-MESP2 monoclonal antibody, clone 2C4G0?
A: Yes, the buffer formulation for Anti-MESP2 monoclonal antibody, clone 2C4G0 is supplied in Preservative: 0.05% Sodium azide; Constituent: 99% PBS. Note: Contains 0.5% protein stabilizer.
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