Specifications
Immunogen
A synthetic peptide of human MED24 is used for rabbit immunization.
Target
Alternative Names
MED24; mediator complex subunit 24; cofactor required for Sp1 transcriptional activation, subunit 4, 100kDa , CRSP4, THRAP4, thyroid hormone receptor associated protein 4; mediator of RNA polymerase II transcription subunit 24; CRSP100; DRIP100; KIAA0130;
Product Background
Antigen Description
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene.
Pathway
Developmental Biology, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem;
Citations
Publication ()
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