Synthetic peptide corresponding to a region within the internal sequence amino acids 93-142 (SVNEAIDQRN QQLRTLQEEC DRKLITLRDE ISIDLYELEE EYYSSSSSLC) of the Human SURF5 protein (NP_598395).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
MED22; mediator complex subunit 22; MED24; SURF5; surf-5; mediator of RNA polymerase II transcription subunit 22; surfeit locus protein 5;
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Pathway
Developmental Biology; Metabolism; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation
Citations
Publication ()
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