Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PCQAP/ MED15 aa 550-650. The exact sequence is proprietary.Database link: Q96RN5
Applications
Application Notes
WB: 1/1000 - 1/2000; IHC-P: 1/100 - 1/250; ICC/IF: 1/50 - 1/100; Flow Cyt: 1/50;
Target
Alternative Names
MED15; mediator complex subunit 15; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q rich associated protein , PCQAP, TNRC7, trinucleotide repeat containing 7; mediator of RNA polymerase II transcription subunit 15; Arc105; CAG7A; TIG 1; TPA i
Product Background
Antigen Description
PCQAP / MED15 is a member of the mediator complex that can act as both a positive and negative regulator of transcription. The mediator complex interacts with RNA pol II and its associated proteins, the general transcription factors. Mediator proteins serve as a bridge connecting the activator and basal transcription machinery.
Pathway
Developmental Biology, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem;
Citations
Publication ()
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COA
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