Anti-MARS2 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human MARS2 aa 1-693.Sequence: MLRTSVLRLLGRTGASRLSLLEDFGPRYYSSGSLSAGDDACDVRAYFTTP IFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQ QAAATAGLAPTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHF WGVLKSRGLLYKGVYEGWYCAS

Conjugate

Application Notes

WB: 1 μg/ml;

Alternative Names

MARS2; methionyl-tRNA synthetase 2, mitochondrial; MetRS; mtMetRS; methionine--tRNA ligase, mitochondrial; methionine--tRNA ligase 2; methionine tRNA ligase 2, mitochondrial; methionine-tRNA synthetase 2, mitochondrial;

Entrez Gene ID

UniProt ID

Antigen Description

MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).[supplied by OMIM, Apr 2010]

Pathway

Aminoacyl-tRNA biosynthesis; Aminoacyl-tRNA biosynthesis, eukaryotes; Gene Expression; Selenocompound metabolism