Rabbit Anti-Human MARCH5 (center) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MARCH5.

Conjugate

Application Notes

WB: 1:500-1:1000
IF/ICC: 1:100-1:500

General Notes

This product (Catalog No. DPABH-11384) is a rabbit-derived polyclonal antibody raised against human MARCH5. This antibody exhibits cross-reactivity with MARCH5 from mouse and rat. It has been affinity purified by Protein A. MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).
DPABH-11384 is suitable for use in Western blot (WB) (1:500–1:1,000), IF/ICC (1:100–1:500) applications.
DPABH-11384 is supplied as a liquid formulation in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

RNF153; E3 ubiquitin-protein ligase MARCH5; Membrane-associated RING finger protein 5; Membrane-associated RING-CH protein V; MARCH-V; Mitochondrial ubiquitin ligase; MITOL; RING finger protein 153

Entrez Gene ID

UniProt ID