Synthetic peptide: GFVIPDEGGPQEEQEEY conjugated to KLH, corresponding to C terminal amino acids 252-268 of Human MAPRE1
Conjugate
Unconjugated
Applications
Application Notes
ICC/IF: 1 - 2 μg/ml. IP: 10-20 ug of the antibody can immunoprecipitate EB1 from a cell lysate of HeLa cells; WB: 0.5 - 1 μg/ml
Target
Alternative Names
MAPRE1; microtubule-associated protein, RP/EB family, member 1; microtubule-associated protein RP/EB family member 1; adenomatous polyposis coli binding protein EB1; EB1; end-binding protein 1; APC-binding protein EB1; adenomatous polyposis coli-binding p
May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
Pathway
Cell Cycle; Cell Cycle, Mitotic; Centrosome maturation; DNA Replication; G2/M Transition; Loss of Nlp from mitotic centrosomes; Loss of proteins required for interphase microtubule organization??from the centrosome
Citations
Publication ()
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COA
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