Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Pathway
Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Adrenergic signaling in cardiomyocytes; Amyotrophic lateral sclerosis (ALS); Cell-Cell communication.
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