AQPEP is a protein-coding gene. Diseases associated with AQPEP include chronic laryngitis, and hypopharynx cancer. GO annotations related to this gene include metalloendopeptidase activity and zinc ion binding. An important paralog of this gene is LNPEP. Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.
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