Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human LSM10 aa 50 to the C-terminus. The exact sequence is proprietary.Database link: Q969L4
Applications
Application Notes
IP: 1/40; WB: 1/5000 - 1/10000.
Target
Alternative Names
LSM10; LSM10, U7 small nuclear RNA associated; U7 snRNA-associated Sm-like protein LSm10; MGC15749; U7 snRNP-specific Sm-like protein LSM10; MST074; MSTP074;
Product Background
Antigen Description
LSM10 is a 14 kDa polypeptide that is a member of the Sm/Lsm protein family. Like U7 snRNA, LSM10 is enriched in Cajal or coiled bodies (CBs) in the nucleus. LSM10 associates with the U7 snRNP and this interaction is dictated by the special Sm binding site of U7 snRNA.
Pathway
Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intronless Pre-mRNA, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem; RNA Polymerase II Transcription Termination, organism-specific biosystem; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs, organism-specific biosystem; SLBP independent Processing of Histone Pre-mRNAs, organism-specific biosystem;
Citations
Publication ()
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