Anti-LRFN2 polyclonal antibody (DPABH-23481)
Rabbit anti-Human LRFN2 (C-terminal) polyclonal antibody for ICC/IF, IHC-P, WB
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Mouse, Rat, Human
Synthetic peptide corresponding to 14 aa from near the C-terminus of Human LRFN2 (Q9ULH4).
ICC/IF: 20μg/ml; IHC-P: 2.5μg/ml; WB: 1 - 2μg/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
LRFN2; leucine rich repeat and fibronectin type III domain containing 2; SALM1; FIGLER2; KIAA1246; leucine-rich repeat and fibronectin type-III domain-containing protein 2
Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery.
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Morimura, N; Katayama, K; et al. Lrfn2/SALM1, a synaptic leucine-rich repeat-containing transmembrane protein regulates synapse formation and function. NEUROSCIENCE RESEARCH 58:S44-S44(2007).
Morimura, N; Yasuda, H; et al. Lrfn2/SALM1 regulates excitatory synapse function in the hippocampus and its deficient mice display mental disorder-like behavioral abnormalities. NEUROSCIENCE RESEARCH 71:E17-E17(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.